Herpes Simplex Infection in Cardiovascular Disease (CVD) Patients: A Seroepidemiological Study

Background: Herpes simplex viruses have been implicated as a cause of cardiovascular disease (CVD) due to their widespread distribution and ability infect human vascular endothelial cells. Objectives: The present study aimed evaluate the link between infections disease. Methods: This case-control involved 236 patients aged 35 - 65, 118 with known controls. Patients’ evaluation was based on data from questionnaires, specialist’s physical examinations, paraclinical tests. (HSV)-antibodies (IgM, IgG) were determined using ELISA in serum samples, biochemical blood indicators analyzed examine relationship level HSV antibodies. All SPSS software version 20. Results: IgM antibodies against herpes negative among all patients. positivity rate IgG 58.8 51.2% case control groups, respectively no significant difference (P = 0.253). Patients had 0.587-fold higher positive than group (odds ratio (OR) 0.587). mean age significantly lower 0.012). men women 0.670) different job statuses 0.866) not different. Conclusions: groups. Although antibodies’ those antibodies, gender status